Sang-Woo Lee Selected Research

sodium-iodide symporter (sodium iodide symporter)

1/2020	A Novel Tyrosine Kinase Inhibitor Can Augment Radioactive Iodine Uptake Through Endogenous Sodium/Iodide Symporter Expression in Anaplastic Thyroid Cancer.
1/2019	A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
1/2018	Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system.
11/2015	Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells.
12/2013	Dual reporter gene imaging for tracking macrophage migration using the human sodium iodide symporter and an enhanced firefly luciferase in a murine inflammation model.
1/2013	Enhancement of natural killer cell cytotoxicity by sodium/iodide symporter gene-mediated radioiodine pretreatment in breast cancer cells.
12/2011	Combined E7-dendritic cell-based immunotherapy and human sodium/iodide symporter radioiodine gene therapy with monitoring of antitumor effects by bioluminescent imaging in a mouse model of uterine cervical cancer.
11/2011	Combined RNA interference of hexokinase II and (131)I-sodium iodide symporter gene therapy for anaplastic thyroid carcinoma.
1/2011	Combined Cerenkov luminescence and nuclear imaging of radioiodine in the thyroid gland and thyroid cancer cells expressing sodium iodide symporter: initial feasibility study.
12/2010	Human sodium iodide symporter added to multidrug resistance 1 small hairpin RNA in a single gene construct enhances the therapeutic effects of radioiodine in a nude mouse model of multidrug resistant colon cancer.

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Sang-Woo Lee Research Topics

Disease

60	Neoplasms (Cancer) 12/2023 - 04/2009
27	Thyroid Neoplasms (Thyroid Cancer) 01/2024 - 04/2007
12	Anaplastic Thyroid Carcinoma 01/2021 - 01/2011
11	Neoplasm Metastasis (Metastasis) 01/2024 - 05/2011
10	Breast Neoplasms (Breast Cancer) 11/2020 - 09/2012
9	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/2023 - 12/2011
9	Papillary Thyroid Cancer 08/2022 - 05/2011
6	Inflammation (Inflammations) 01/2020 - 11/2011
5	Hepatocellular Carcinoma (Hepatoma) 02/2017 - 04/2010
3	B-Cell Lymphoma (Lymphoma, B Cell) 02/2024 - 01/2019
3	Infections 01/2022 - 07/2011
3	Rectal Neoplasms (Rectal Cancer) 09/2021 - 04/2011
3	Glioblastoma (Glioblastoma Multiforme) 11/2020 - 01/2018
3	Colonic Neoplasms (Colon Cancer) 03/2018 - 12/2010
3	Carcinoma (Carcinomatosis) 01/2018 - 11/2011
2	Lung Neoplasms (Lung Cancer) 02/2024 - 01/2017
2	Melanoma (Melanoma, Malignant) 12/2023 - 01/2017
2	Mouth Neoplasms (Oral Cancer) 09/2023 - 09/2023
2	Hypertension (High Blood Pressure) 06/2022 - 11/2011
2	Wounds and Injuries (Trauma) 03/2022 - 09/2018
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2019
2	Ischemia 01/2020 - 10/2017
2	Necrosis 09/2018 - 01/2013
2	Lymphatic Metastasis 01/2018 - 01/2015
2	Adenocarcinoma 01/2015 - 04/2009
2	Glioma (Gliomas) 07/2014 - 01/2014
1	Rheumatic Diseases (Rheumatism) 02/2024
1	Human Influenza (Influenza) 02/2024
1	Dysentery 02/2024
1	Liver Diseases (Liver Disease) 02/2024
1	Asthma (Bronchial Asthma) 12/2023
1	Bronchitis 12/2023
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 12/2023
1	Dental Caries (Decay, Dental) 01/2023
1	Spinal Cord Injuries (Spinal Cord Injury) 09/2022
1	Neuralgia (Stump Neuralgia) 09/2022
1	Hypersensitivity (Allergy) 09/2022

Drug/Important Bio-Agent (IBA)

20	IodineIBA 01/2024 - 04/2009
15	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 08/2021 - 09/2012
10	Therapeutic UsesIBA 01/2020 - 12/2010
10	sodium-iodide symporter (sodium iodide symporter)IBA 01/2020 - 12/2010
7	Renilla LuciferasesIBA 10/2018 - 12/2010
6	Thyroglobulin FDA Link 12/2023 - 09/2014
6	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2013
4	Thyrotropin Alfa FDA LinkGeneric 01/2024 - 12/2015
4	Caspase 3 (Caspase-3)IBA 01/2018 - 01/2014
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2015
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 05/2010
4	Firefly LuciferasesIBA 10/2017 - 12/2011
4	Small Interfering RNA (siRNA)IBA 11/2013 - 12/2010
3	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2024 - 12/2015
3	Thyroid HormonesIBA 01/2024 - 10/2017
3	piperlongumineIBA 12/2023 - 09/2023
3	GoldIBA 01/2021 - 01/2017
3	Tyrosine Kinase InhibitorsIBA 11/2020 - 01/2018
3	Ganciclovir (Cytovene)FDA LinkGeneric 03/2018 - 05/2010
3	SymportersIBA 10/2017 - 04/2010
3	Radioisotopes (Radionuclides)IBA 01/2017 - 04/2010
3	Estrogen ReceptorsIBA 10/2015 - 06/2011
3	Progesterone Receptors (Progesterone Receptor)IBA 10/2015 - 06/2011
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 02/2024 - 10/2023
2	AmidesIBA 12/2023 - 10/2023
2	AlkaloidsIBA 12/2023 - 10/2023
2	Antineoplastic Agents (Antineoplastics)IBA 10/2023 - 09/2023
2	Amyloid (Amyloid Fibrils)IBA 01/2022 - 09/2013
2	Hormones (Hormone)IBA 11/2020 - 10/2015
2	human ERBB2 proteinIBA 11/2020 - 09/2012
2	Estrogens (Estrogen)FDA Link 01/2019 - 11/2015
2	AntigensIBA 01/2019 - 12/2011
2	IodidesIBA 01/2019 - 11/2011
2	Diphosphonates (Bisphosphonates)IBA 08/2018 - 09/2012
2	ProdrugsIBA 03/2018 - 04/2010
2	Sincalide FDA Link 01/2018 - 01/2017
2	SodiumIBA 10/2017 - 04/2010
2	Sodium Pertechnetate Tc 99m (Pertechnetate)FDA Link 10/2017 - 04/2007
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2017 - 10/2015
2	CarrageenanIBA 01/2017 - 10/2015
2	SolutionsIBA 10/2015 - 12/2004
2	LigandsIBA 01/2014 - 11/2011
2	Peptides (Polypeptides)IBA 09/2013 - 11/2011
1	Plant ExtractsIBA 02/2024
1	UraniumIBA 12/2023
1	DAPIIBA 10/2023
1	Annexin A5IBA 10/2023
1	Propidium (Propidium Iodide)IBA 10/2023
1	piperineIBA 09/2023
1	Autophagy-Related ProteinsIBA 09/2023
1	Serine (L-Serine)FDA Link 09/2022
1	N-Methylaspartate (NMDA)IBA 09/2022
1	Dizocilpine Maleate (Dizocilpine)IBA 09/2022

Therapy/Procedure

40	Therapeutics 01/2024 - 04/2007
7	Thyroidectomy 01/2022 - 04/2007
7	Chemoradiotherapy 06/2020 - 05/2013
6	Immunotherapy 01/2019 - 12/2011
5	Neoadjuvant Therapy 09/2021 - 05/2013
3	Drug Therapy (Chemotherapy) 01/2018 - 04/2010
2	Precision Medicine 08/2021 - 05/2019
2	Massage (Zone Therapy) 08/2019 - 11/2014
2	Lasers (Laser) 05/2019 - 05/2004
1	Orthodontic Brackets 01/2023